The main innovative aspect of SIRIO, compared with traditional techniques, is that it shows patient’s internal tissues and organs in real time.

Therefore, the interventional physician no longer needs to mentally plan the whole procedure based only on CT or RM bi-dimensional images: thanks to SIRIO, he can identify the target and reach it with the surgical tool in the CT/RM room during operation.

SIRIO consists of:

  • processing unit for 3D reconstruction of the relevant anatomical district;
  • an infrared localization system, detecting the position and orientation of the surgical needle relatively to the patient;
  • the disposable sterile kit, allowing the infrared system to localize the surgical tools and the patient’s position;
  • the breathing sensor for displacement monitoring of the patient's rib cage.

Simple use

Great attention was paid to designing a clear and intuitive user interface and setting intelligent procedures: registration and calibration are carried out automatically, efficiently and quickly and are completely transparent to the user. For this reason, SIRIO does not require long training sessions nor specific technical expertise to be used.

Furthermore, after launching the application, no interaction with the system is needed by mouse or keyboard, so the physician can perform all the procedures keeping his hands within the surgical sterile field.

Customization of images

The views provided by the device come from 3D reconstruction through proprietary algorithms to guarantee high quality and reliability. Images and projections can be customized according to the type of surgery or personal preferences.

Maximum patient safety

By means of the breathing sensor and advanced algorithms, SIRIO monitors the movements of the patient's rib cage and the postural variations that may occur. Hence the system is suitable for different anatomical districts, including the pulmonary one.

In case of a control CT-scan during surgery, the 3D model can be rapidly updated with the new images to get the best approximation to the real situation.


SIRIO is compatible with all the tomographic imaging systems based on the DICOM protocol. It can be used to track any kind of needle or surgical rigid instrument (cannula, endoscope) with a diameter size ranging from 11G to 22G through the universal adapter.



SIRIO enables to reach deep targets by percutaneous access, cutting back the risk of injuring important anatomical structures. The system was conceived for the pulmonary district but it goes through continuous evolution: MASMEC Biomed bioengineers are now working to widen the application to other districts such as abdomen and skull base.

Possible applications are: biopsy, thermal ablation, vertebroplasty, laparoscopy, biliary drainage, fluid aspiration, deep drug infusion, access to deep vessels/areas and anaesthesia and pain therapy.


Clinical procedure

SIRIO must be used with the kit for surgical procedures provided by MASMEC Biomed. The kit allows to localize and track in real time the surgical tools relatively to the patient’s position through the IR sensor.

It is sterile and disposable and consists of:

  • patient sensor for monitoring of patient’s position;
  • needle sensor for tracking of needle position and orientation;
  • needle guide for identification and mechanical stabilization of insertion trajectory;
  • direction tool for selection of the best insertion trajectory.


The system can also monitor the movements of the patient’s rib cage in real time by means of the breathing sensor. The screen will show the variation between the current breathing level and the one registered during CT scan.



SIRIO was developed to improve procedure efficacy and patient care.

Benefits for the physician

  • Pre-operative planning through 3D models
  • Minimum encumbrance of the surgical field
  • Higher sample success rate
  • Better reliability and repeatability of surgical procedures
  • Training mode
  • Simple and clear use

Benefits for the patient

  • Consistent reduction of absorbed ionizing radiation dose
  • Reduced intervention time
  • Improved efficacy of biopsy and thermal ablation procedures

Benefits for the hospital

  • Reduced time of CT room occupancy
  • Higher number of patients treated
  • Improved workflow


SIRIO has been successfully used on hundreds of patients so far, most of all for early diagnosis of lung cancer.

It is scientifically proven that this system allows to reduce both intervention duration and CT scans by more than 40%. A decrease in post-operative complications (pnx) is demonstrated as well.

“SIRIO helps reach the lesion in less time, with a reduced number of CT scans and a lower radiation dose for the patient. Furthermore SIRIO shows the correct trajectory of the needle with a higher accuracy than the traditional methods."*